作者：Xiao Wang, Shao-Ping Nie
单位：Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China
通讯作者：聂绍平 Shao-Ping Nie, MD, PhD.
通讯地址：中国北京 朝阳区 安贞路2号 首都医科大学 北京安贞医院 心内科Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, No. 2 Anzhen Road, Chaoyang District, Beijing 100029, China. Tel: +86-10-64456372; Fax: +86-10-64456078. Email: spnie@126.com.
摘要：冠状慢血流现象(CSFP)是一种重要的血管造影并发症，表现为造影剂注入并通过冠状动脉的过程中发生灌注延迟现象。这是一种常见病，尤其是在急性冠状动脉综合征患者当中。虽然这种病已有近40年历史，其发病机理仍然不太清楚。超过80%的患者会频繁出现胸痛，给生活质量带来显著损害，因此针对该病的研究具有重要意义。本文将详细陈述该病的特点、可能的发病机制以及临床症状表现，深入讨论其临床意义和治疗对策。
关键词：冠状动脉慢血流现象；冠状动脉树；胸痛
The coronary slow flow phenomenon: Characteristics, mechanisms and implications
Xiao Wang, Shao-Ping Nie
Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China
Corresponding to: Shao-Ping Nie, MD, PhD. Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, No. 2 Anzhen Road, Chaoyang District, Beijing 100029, China. Tel: +86-10-64456372; Fax: +86-10-64456078. Email: spnie@126.com.
Abstract
The coronary slow flow phenomenon (CSFP)is an important, angiographic entity characterized by delayed progression of the injected contrast medium through the coronary tree. It is a frequent finding, typically observed in patients presenting with acute coronary syndromes. Although it is well know to interventional cardiologists for approximately four decades, the pathogenic mechanisms remain unclear. The clinical implications are significant, with over 80% of patients experiencing recurrent chest pain, resulting in considerable impairment in quality of life. This article will address in detail the characteristics, possible mechanisms, and clinical implications of this entity to provide further insight into its clinical significance and management strategies.
